MUC12
MUC12 (англ. Mucin 12, cell surface associated) – білок, який кодується однойменним геном, розташованим у людей на 7-й хромосомі.[2] Довжина поліпептидного ланцюга білка становить 5 478 амінокислот, а молекулярна маса — 558 164[3].
Послідовність амінокислот
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MLVIWILTLA | LRLCASVTTV | TPEGSAVHKA | ISQQGTLWTG | EVLEKQTVEQ | ||||
| GKSTLRRQKN | HFHRSAGELR | CRNALKDEGA | SAGWSVMFAG | ESVVVLVHLW | ||||
| MTGARVKNLG | LVEFASPGDD | GDGRAEGFSL | GLPLSEQARA | AGAREKERQE | ||||
| TVINHSTFSG | FSQITGSTVN | TSIGGNTTSA | STPSSSDPFT | TFSDYGVSVT | ||||
| FITGSTATKH | FLDSSTNSGH | SEESTVSHSG | PGATGTTLFP | SHSATSVFVG | ||||
| EPKTSPITSA | SMETTALPGS | TTTAGLSEKS | TTFYSSPRSP | DRTLSPARTT | ||||
| SSGVSEKSTT | SHSRPGPTHT | IAFPDSTTMP | GVSQESTASH | SIPGSTDTTL | ||||
| SPGTTTPSSL | GPESTTFHSS | PGYTKTTRLP | DNTTTSGLLE | ASTPVHSSTG | ||||
| SPHTTLSPSS | STTHEGEPTT | FQSWPSSKDT | SPAPSGTTSA | FVKLSTTYHS | ||||
| SPSSTPTTHF | SASSTTLGHS | EESTPVHSSP | VATATTPPPA | RSATSGHVEE | ||||
| STAYHRSPGS | TQTMHFPESS | TTSGHSEESA | TFHGSTTHTK | SSTPSTTAAL | ||||
| AHTSYHSSLG | STETTHFRDS | STISGRSEES | KASHSSPDAM | ATTVLPAGST | ||||
| PSVLVGDSTP | SPISSGSMET | TALPGSTTKP | GLSEKSTTFY | SSPRSPDTTH | ||||
| LPASMTSSGV | SEESTTSHSR | PGSTHTTAFP | GSTTMPGLSQ | ESTASHSSPG | ||||
| PTDTTLSPGS | TTASSLGPEY | TTFHSRPGST | ETTLLPDNTT | ASGLLEASMP | ||||
| VHSSTRSPHT | TLSPAGSTTR | QGESTTFHSW | PSSKDTRPAP | PTTTSAFVEP | ||||
| STTSHGSPSS | IPTTHISARS | TTSGLVEEST | TYHSSPGSTQ | TMHFPESDTT | ||||
| SGRGEESTTS | HSSTTHTISS | APSTTSALVE | EPTSYHSSPG | STATTHFPDS | ||||
| STTSGRSEES | TASHSSQDAT | GTIVLPARST | TSVLLGESTT | SPISSGSMET | ||||
| TALPGSTTTP | GLSERSTTFH | SSPRSPATTL | SPASTTSSGV | SEESTTSRSR | ||||
| PGSTHTTAFP | DSTTTPGLSR | HSTTSHSSPG | STDTTLLPAS | TTTSGPSQES | ||||
| TTSHSSSGST | DTALSPGSTT | ALSFGQESTT | FHSNPGSTHT | TLFPDSTTSS | ||||
| GIVEASTRVH | SSTGSPRTTL | SPASSTSPGL | QGESTAFQTH | PASTHTTPSP | ||||
| PSTATAPVEE | STTYHRSPGS | TPTTHFPASS | TTSGHSEKST | IFHSSPDASG | ||||
| TTPSSAHSTT | SGRGESTTSR | ISPGSTEITT | LPGSTTTPGL | SEASTTFYSS | ||||
| PRSPTTTLSP | ASMTSLGVGE | ESTTSRSQPG | STHSTVSPAS | TTTPGLSEES | ||||
| TTVYSSSRGS | TETTVFPHST | TTSVHGEEPT | TFHSRPASTH | TTLFTEDSTT | ||||
| SGLTEESTAF | PGSPASTQTG | LPATLTTADL | GEESTTFPSS | SGSTGTKLSP | ||||
| ARSTTSGLVG | ESTPSRLSPS | STETTTLPGS | PTTPSLSEKS | TTFYTSPRSP | ||||
| DATLSPATTT | SSGVSEESST | SHSQPGSTHT | TAFPDSTTTS | DLSQEPTTSH | ||||
| SSQGSTEATL | SPGSTTASSL | GQQSTTFHSS | PGDTETTLLP | DDTITSGLVE | ||||
| ASTPTHSSTG | SLHTTLTPAS | STSAGLQEES | TTFQSWPSSS | DTTPSPPGTT | ||||
| AAPVEVSTTY | HSRPSSTPTT | HFSASSTTLG | RSEESTTVHS | SPGATGTALF | ||||
| PTRSATSVLV | GEPTTSPISS | GSTETTALPG | STTTAGLSEK | STTFYSSPRS | ||||
| PDTTLSPAST | TSSGVSEEST | TSHSRPGSTH | TTAFPGSTTM | PGVSQESTAS | ||||
| HSSPGSTDTT | LSPGSTTASS | LGPESTTFHS | SPGSTETTLL | PDNTTASGLL | ||||
| EASTPVHSST | GSPHTTLSPA | GSTTRQGEST | TFQSWPSSKD | TMPAPPTTTS | ||||
| AFVELSTTSH | GSPSSTPTTH | FSASSTTLGR | SEESTTVHSS | PVATATTPSP | ||||
| ARSTTSGLVE | ESTAYHSSPG | STQTMHFPES | STASGRSEES | RTSHSSTTHT | ||||
| ISSPPSTTSA | LVEEPTSYHS | SPGSTATTHF | PDSSTTSGRS | EESTASHSSQ | ||||
| DATGTIVLPA | RSTTSVLLGE | STTSPISSGS | METTALPGST | TTPGLSEKST | ||||
| TFHSSPRSPA | TTLSPASTTS | SGVSEESTTS | HSRPGSTHTT | AFPDSTTTPG | ||||
| LSRHSTTSHS | SPGSTDTTLL | PASTTTSGPS | QESTTSHSSP | GSTDTALSPG | ||||
| STTALSFGQE | STTFHSSPGS | THTTLFPDST | TSSGIVEAST | RVHSSTGSPR | ||||
| TTLSPASSTS | PGLQGESTAF | QTHPASTHTT | PSPPSTATAP | VEESTTYHRS | ||||
| PGSTPTTHFP | ASSTTSGHSE | KSTIFHSSPD | ASGTTPSSAH | STTSGRGEST | ||||
| TSRISPGSTE | ITTLPGSTTT | PGLSEASTTF | YSSPRSPTTT | LSPASMTSLG | ||||
| VGEESTTSRS | QPGSTHSTVS | PASTTTPGLS | EESTTVYSSS | PGSTETTVFP | ||||
| RTPTTSVRGE | EPTTFHSRPA | STHTTLFTED | STTSGLTEES | TAFPGSPAST | ||||
| QTGLPATLTT | ADLGEESTTF | PSSSGSTGTT | LSPARSTTSG | LVGESTPSRL | ||||
| SPSSTETTTL | PGSPTTPSLS | EKSTTFYTSP | RSPDATLSPA | TTTSSGVSEE | ||||
| SSTSHSQPGS | THTTAFPDST | TTPGLSRHST | TSHSSPGSTD | TTLLPASTTT | ||||
| SGPSQESTTS | HSSPGSTDTA | LSPGSTTALS | FGQESTTFHS | SPGSTHTTLF | ||||
| PDSTTSSGIV | EASTRVHSST | GSPRTTLSPA | SSTSPGLQGE | STTFQTHPAS | ||||
| THTTPSPPST | ATAPVEESTT | YHRSPGSTPT | THFPASSTTS | GHSEKSTIFH | ||||
| SSPDASGTTP | SSAHSTTSGR | GESTTSRISP | GSTEITTLPG | STTTPGLSEA | ||||
| STTFYSSPRS | PTTTLSPASM | TSLGVGEEST | TSRSQPGSTH | STVSPASTTT | ||||
| PGLSEESTTV | YSSSPGSTET | TVFPRSTTTS | VRGEEPTTFH | SRPASTHTTL | ||||
| FTEDSTTSGL | TEESTAFPGS | PASTQTGLPA | TLTTADLGEE | STTFPSSSGS | ||||
| TGTTLSPARS | TTSGLVGEST | PSRLSPSSTE | TTTLPGSPTT | PSLSEKSTTF | ||||
| YTSPRSPDAT | LSPATTTSSG | VSEESSTSHS | QPGSTHTTAF | PDSTTTSGLS | ||||
| QEPTASHSSQ | GSTEATLSPG | STTASSLGQQ | STTFHSSPGD | TETTLLPDDT | ||||
| ITSGLVEAST | PTHSSTGSLH | TTLTPASSTS | AGLQEESTTF | QSWPSSSDTT | ||||
| PSPPGTTAAP | VEVSTTYHSR | PSSTPTTHFS | ASSTTLGRSE | ESTTVHSSPG | ||||
| ATGTALFPTR | SATSVLVGEP | TTSPISSGST | ETTALPGSTT | TAGLSEKSTT | ||||
| FYSSPRSPDT | TLSPASTTSS | GVSEESTTSH | SRPGSTHTTA | FPGSTTMPGV | ||||
| SQESTASHSS | PGSTDTTLSP | GSTTASSLGP | ESTTFHSGPG | STETTLLPDN | ||||
| TTASGLLEAS | TPVHSSTGSP | HTTLSPAGST | TRQGESTTFQ | SWPNSKDTTP | ||||
| APPTTTSAFV | ELSTTSHGSP | SSTPTTHFSA | SSTTLGRSEE | STTVHSSPVA | ||||
| TATTPSPARS | TTSGLVEEST | TYHSSPGSTQ | TMHFPESDTT | SGRGEESTTS | ||||
| HSSTTHTISS | APSTTSALVE | EPTSYHSSPG | STATTHFPDS | STTSGRSEES | ||||
| TASHSSQDAT | GTIVLPARST | TSVLLGESTT | SPISSGSMET | TALPGSTTTP | ||||
| GLSEKSTTFH | SSPRSPATTL | SPASTTSSGV | SEESTTSHSR | PGSTHTTAFP | ||||
| DSTTTPGLSR | HSTTSHSSPG | STDTTLLPAS | TTTSGSSQES | TTSHSSSGST | ||||
| DTALSPGSTT | ALSFGQESTT | FHSSPGSTHT | TLFPDSTTSS | GIVEASTRVH | ||||
| SSTGSPRTTL | SPASSTSPGL | QGESTAFQTH | PASTHTTPSP | PSTATAPVEE | ||||
| STTYHRSPGS | TPTTHFPASS | TTSGHSEKST | IFHSSPDASG | TTPSSAHSTT | ||||
| SGRGESTTSR | ISPGSTEITT | LPGSTTTPGL | SEASTTFYSS | PRSPTTTLSP | ||||
| ASMTSLGVGE | ESTTSRSQPG | STHSTVSPAS | TTTPGLSEES | TTVYSSSPGS | ||||
| TETTVFPRST | TTSVRREEPT | TFHSRPASTH | TTLFTEDSTT | SGLTEESTAF | ||||
| PGSPASTQTG | LPATLTTADL | GEESTTFPSS | SGSTGTKLSP | ARSTTSGLVG | ||||
| ESTPSRLSPS | STETTTLPGS | PTTPSLSEKS | TTFYTSPRSP | DATLSPATTT | ||||
| SSGVSEESST | SHSQPGSTHT | TAFPDSTTTS | GLSQEPTTSH | SSQGSTEATL | ||||
| SPGSTTASSL | GQQSTTFHSS | PGDTETTLLP | DDTITSGLVE | ASTPTHSSTG | ||||
| SLHTTLTPAS | STSTGLQEES | TTFQSWPSSS | DTTPSPPSTT | AVPVEVSTTY | ||||
| HSRPSSTPTT | HFSASSTTLG | RSEESTTVHS | SPGATGTALF | PTRSATSVLV | ||||
| GEPTTSPISS | GSTETTALPG | STTTAGLSEK | STTFYSSPRS | PDTTLSPAST | ||||
| TSSGVSEEST | TSHSRPGSMH | TTAFPSSTTM | PGVSQESTAS | HSSPGSTDTT | ||||
| LSPGSTTASS | LGPESTTFHS | SPGSTETTLL | PDNTTASGLL | EASTPVHSST | ||||
| GSPHTTLSPA | GSTTRQGEST | TFQSWPNSKD | TTPAPPTTTS | AFVELSTTSH | ||||
| GSPSSTPTTH | FSASSTTLGR | SEESTTVHSS | PVATATTPSP | ARSTTSGLVE | ||||
| ESTTYHSSPG | STQTMHFPES | NTTSGRGEES | TTSHSSTTHT | ISSAPSTTSA | ||||
| LVEEPTSYHS | SPGSTATTHF | PDSSTTSGRS | EESTASHSSQ | DATGTIVLPA | ||||
| RSTTSVLLGE | STTSPISSGS | METTALPGST | TTPGLSEKST | TFHSSPSSTP | ||||
| TTHFSASSTT | LGRSEESTTV | HSSPVATATT | PSPARSTTSG | LVEESTAYHS | ||||
| SPGSTQTMHF | PESSTASGRS | EESRTSHSST | THTISSPPST | TSALVEEPTS | ||||
| YHSSPGSIAT | THFPESSTTS | GRSEESTASH | SSPDTNGITP | LPAHFTTSGR | ||||
| IAESTTFYIS | PGSMETTLAS | TATTPGLSAK | STILYSSSRS | PDQTLSPASM | ||||
| TSSSISGEPT | SLYSQAESTH | TTAFPASTTT | SGLSQESTTF | HSKPGSTETT | ||||
| LSPGSITTSS | FAQEFTTPHS | QPGSALSTVS | PASTTVPGLS | EESTTFYSSP | ||||
| GSTETTAFSH | SNTMSIHSQQ | STPFPDSPGF | THTVLPATLT | TTDIGQESTA | ||||
| FHSSSDATGT | TPLPARSTAS | DLVGEPTTFY | ISPSPTYTTL | FPASSSTSGL | ||||
| TEESTTFHTS | PSFTSTIVST | ESLETLAPGL | CQEGQIWNGK | QCVCPQGYVG | ||||
| YQCLSPLESF | PVETPEKLNA | TLGMTVKVTY | RNFTEKMNDA | SSQEYQNFST | ||||
| LFKNRMDVVL | KGDNLPQYRG | VNIRRLLNGS | IVVKNDVILE | ADYTLEYEEL | ||||
| FENLAEIVKA | KIMNETRTTL | LDPDSCRKAI | LCYSEEDTFV | DSSVTPGFDF | ||||
| QEQCTQKAAE | GYTQFYYVDV | LDGKLACVNK | CTKGTKSQMN | CNLGTCQLQR | ||||
| SGPRCLCPNT | NTHWYWGETC | EFNIAKSLVY | GIVGAVMAVL | LLALIILIIL | ||||
| FSLSQRKRHR | EQYDVPQEWR | KEGTPGIFQK | TAIWEDQNLR | ESRFGLENAY | ||||
| NNFRPTLETV | DSGTELHIQR | PEMVASTV |
| MUC12 | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ідентифікатори | |||||||||||||||||
| Символи | MUC12, MUC-11, MUC-12, MUC11, mucin 12, cell surface associated | ||||||||||||||||
| Зовнішні ІД | OMIM: 604609 HomoloGene: 130050 GeneCards: MUC12 | ||||||||||||||||
| |||||||||||||||||
| Ортологи | |||||||||||||||||
| Види | Людина | Миша | |||||||||||||||
| Entrez |
|
| |||||||||||||||
| Ensembl |
|
| |||||||||||||||
| UniProt |
|
| |||||||||||||||
| RefSeq (мРНК) |
|
| |||||||||||||||
| RefSeq (білок) |
|
| |||||||||||||||
| Локус (UCSC) | Хр. 7: 100.97 – 101.02 Mb | н/д | |||||||||||||||
| PubMed search | [1] | н/д | |||||||||||||||
| Вікідані | |||||||||||||||||
| |||||||||||||||||
Задіяний у такому біологічному процесі, як альтернативний сплайсинг. Локалізований у мембрані.
Література
- Lievin-Le Moal V., Servin A.L., Coconnier-Polter M.-H. (2005). The increase in mucin exocytosis and the upregulation of MUC genes encoding for membrane-bound mucins induced by the thiol-activated exotoxin listeriolysin O is a host cell defence response that inhibits the cell-entry of Listeria monocytogenes.. Cell. Microbiol. 7: 1035 — 1048. PubMed DOI:10.1111/j.1462-5822.2005.00532.x
Примітки
- Human PubMed Reference:.
- HUGO Gene Nomenclature Commitee, HGNC:7510 (англ.). Процитовано 19 вересня 2017.
- UniProt, Q9UKN1 (англ.). Процитовано 19 вересня 2017.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.